Roller Compacted Concrete is a mixture of cement, aggregates, and low water content mixed in a continuous mix pug mill. Cost savings in using RCC are achieved from faster production rates, no reinforcing steel used, and reduced labor costs. The end product is a compacted, durable, high strength concrete.
We used micro-CT to assess uniformity of density of simulated ribbon, taking advantage of its capability for density quantitation [17, 20, [33], [34], [35]].Ribbon images were reconstructed from raw X-ray micro-CT data, which showed relatively uniform density in the simulated ribbon (Fig. 2 a).The X-ray opacity of Y-Z cross sections of the stacking …
Design of Experiments (DoE) was conducted using three variables: roller compactor type, mill type and target ribbon porosity (Fig. 1).The roller compactors compared in this study were: Gerteis MiniPactor (Gerteis, Rapperswil-Jona, Switzerland), Hosokawa Bepex Pharmapaktor C250/30 (Hosokawa , Leingarten, Germany) and …
The roller compactor (granulator-compactor) uses an auger-feed system that will consistently deliver powder uniformly between two pressure rollers. The powders are compacted into a ribbon or small pellets between …
Corpus ID: 6804652; Density mapping of roller-compacted ribbons using terahertz spectroscopy @inproceedings{Sullivan2011DensityMO, title={Density mapping of roller-compacted ribbons using terahertz spectroscopy}, author={Mark Sullivan and David A. Heaps and Richard McKay and Eiji Kato and Chuan-Yu Wu and Chunlei Pei and …
suitable to roller-compacted concrete, due to the coarse nature of RCC and the ability to achieve high compactive effort in the field through the use of large steel-drum vibratory compactors typically used on RCC projects. Both the standard and modified Proctor tests were developed for soils.The modified Proctor compaction test uses 56,000 ft-lb
Roller-compacted ribbon size reduction is a key operation to produce a granular product suitable for downstream processing. The chapter introduces models to …
Roller compaction uses an auger-feed system that delivers powder uniformly between two pressure rollers. The powder is compacted into a ribbon between these rollers prior to milling through a low-shear mill. Uniform density across the ribbon is critical to achieving granules with a uniform particle size distribution.
Roller compaction is a common unit operation (1,2) used in the pharmaceutical industry to improve the flow properties of powders prior to tableting ().Typically, a formulated blend consisting of active pharmaceutical ingredients (API) and excipients is compacted between two counter-rotating rolls under pressure to form a …
Roller compaction system and ribbon production. The roller compactor was an Alexanderwerk WP120 (Alexanderwerk, Germany), which incorporates a feeding, compaction, and milling system and is equipped with a de-aeration system that can enhance the powder flowability and play a role in reducing the amount of fines.
Roller-compacted ribbon size reduction is a key operation to produce a granular product suitable for downstream processing. The chapter introduces models to describe some of the key unit operations used in pharmaceutical roller compaction-based tablet manufacture.
Roller compaction is a continuous process which means lower operation cost and higher overall process efficiency [1,2]. The main disadvantage of the roller compaction is the large amount of fines that are produced during the production of ribbons [3,4]. Ribbon properties are controlling the quality of the final granules.
Counter-rotating rollers compact powder into ribbon 3. Mill reduces ribbon to granules 4. Optical path of terahertz beam to ribbon ... Of course a roller-compacted ribbon is a porous material
An experiment whereby roll pressure was linearly increased and the effects thereof on roller compacted ribbon and granule properties of a placebo formulation is described.
The choice of powder to be compacted is therefore critical. ... speed was kept constant at 1 rpm and the die fill depth was fixed at 4 mm and 8 mm to produce ribbons with identical ribbon thickness to the mini scale roller compactor settings. ... The ribbon produced by micro scale and mini scale roller compactor was milled using a small-scale ...
Transfer and scale-up of roller compaction processes based on conservation of ribbon density is relatively well established, although different equipment designs, …
The powders are compacted into a ribbon or small pellets between these rollers and milled through a low-shear mill. When the product is compacted properly, then it can be passed through a mill and final blend before tablet compression. A Roller compactor generally consists of three major units:
1. Introduction. Dry granulation technology via roller compaction (RC) is increasingly applied in the pharmaceutical industry to produce solid oral dosage forms, mainly tablets, as well as capsules and sachets (Chang et al., 2008, Lopes et al., 2016).The granulation step primarily addresses the poor flowability of powders and other issues, …
Roller compaction is commonly used in the pharmaceutical industry to densify material to enhance its flow properties and improve content uniformity. Unlike wet granulation, roller compaction does not …
The milling conditions selected for the Gerteis and M5A mill were based on previously established milling parameters used for the size reduction of roller-compacted ribbon. The 0.8-mm screen size selected for both mill types produces satisfactory granules for conventional IR tablet formulations consistently.
Beneath the rolls the resulting ribbon is milled by the in-line mill to produce the final granulate product. Figure 1: Schematic of the Chilsonator roller compaction process. ... Three placebo blends were roller compacted: 99.25% SuperTab 21AN with 0.75% magnesium stearate; 65% SuperTab 21AN with 35% Pharmacel 102; and 55% …
RECENT ADVANCES AND USES OF ROLLER COMPACTED CONCRETE PAVEMENTS IN THE UNITED STATES C. Zollinger Paving Solutions, CEMEX, Inc, Houston, TX USA Coreyj.zollinger@cemex ABSTRACT Roller Compacted Concrete (RCC) is a no slump concrete that is placed by an asphalt paver and compacted with vibratory rollers …
The breakage rates of roller compacted ribbons of two pharmaceutical excipients, microcrystalline cellulose (MCC) and mannitol, were determined with two different approaches, i.e. by analysing the ...
Dry granulation by roller compaction consists of two separate steps. The first step is an agglomeration step, starting From Raw Material Powder to Flake (1.2). The …
During the roller compaction operation, uniformly mixed powder blends are passed continuously through the gap between a pair of counter rotating compression …
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1.. IntroductionRoller compaction is one stage in a continuous dry granulation process for producing free flowing granules. In this process, powder blends are compressed between two counter-rotating rollers to form ribbons, flakes or briquettes, which are then milled to obtain granules [1], [2]pared to other granulation processes, roller …
Roller compaction (RC) is a modern dry granulation process, which involves compressing a powder into ribbons between two rolls. Ribbons are subsequently milled …
Ribbon mills typically comprise a hemicylindrical screen at the base, with side walls and a set of rotating bars or pins that contact the ribbons and shear them against each other and the base. ... Visualization and prediction of porosity in roller compacted ribbons with near-infrared chemical imaging (NIR-CI) J. Pharm. Biomed. Anal. (2015) …
A novel method for estimating solid fraction of roller-compacted ribbons Drug Dev Ind Pharm. 2008 Feb;34(2):142-8. doi: 10.1080/03639040701484387. ... Ribbon relaxation occurring upon ribbon exiting the compaction zone is estimated using roll geometry, roll gap, and ribbon thickness. ...
The Small Scale Mill reproduces the same milling steps as the company's renowned PACTOR® roller compaction machines with almost identical particle size distribution (PSD), making it a highly useful tool for …
